The goal of this cluster is to explore how the understanding of genetics can help to personalize the medical treatments we receive. Learners will examine medical cases, explore how your DNA may make it so things taste different to you than to other people and why, and investigate how we know what genes control what traits. Learners will use biotechnology lab techniques to learn how to extract DNA from cells, amplify the TAS2R38 region using PCR, and analyze that region with restriction enzymes and gel electrophoresis to see what it tells you about one’s ability to taste a particular flavor. For those using this cluster as part of a hybrid ABE experience, please see implementation details in the teaching guides in the pathway, Teaching Guides for the Exploring Precision Medicine Cluster.