Hydrodynamics in a Bioreactor for Culturing Cells

A bioreactor is a cell culture vessel used to incubate cells at a high density. Good mixing is essential to cell survival and is connected to the hydrodynamics (motion of fluids) in a bioreactor. This interactive scrollable reviews the basic components and functions of a bioreactor, explains why good mixing and aeration are essential to cell survival in a bioreactor, and describes how impeller design and agitation rates determine the hydrodynamics in a bioreactor.

Topics

  • ALXCollab
  • agitation rate
  • agitation
  • agitator
  • axial flow impeller
  • axial impeller
  • biologic production
  • biologic
  • bioreactor
  • cell culture medium
  • cell culture
  • cell density
  • cell waste
  • culturing cells
  • drug substance technology
  • drug substance
  • hydrodynamic
  • impeller
  • liquid pump
  • mAb
  • mixing
  • monoclonal antibody
  • nutrient
  • probe
  • radial flow impeller
  • radial impeller
  • sparger
  • therapeutic protein production
  • therapeutic protein
  • thermal jacket
  • tube
  • turbulent flow
  • vessel body