PCR Primer Design

This interactive will present the rules for designing precise nucleotide sequences called PCR primers. Designing primers for a PCR reaction is an important step because the way they bind to the template DNA dictates much of the success of the PCR reaction.

Topics

  • polymerase chain reaction
  • pcr
  • gene
  • amplification
  • denature
  • denaturation
  • pcr product
  • gel electrophoresis
  • dna sequencing
  • dna
  • genome
  • amplified dna
  • pcr cycle
  • template
  • strand
  • forward primer
  • reverse primer
  • lab technique
  • sequence
  • specific sequence
  • nucleotide
  • nucleotide sequence
  • region
  • design
  • primer
  • amplify
  • anneal
  • dna synthesis
  • dna polymerase
  • enzyme
  • reaction
  • pcr reaction
  • complementary base pairing
  • guanines
  • cytosines
  • hydrogen bond
  • taq
  • taq polymerase
  • elongation
  • complementary
  • mismatch
  • mutation
  • base pair
  • base pairing
  • 5’ to 3’
  • 5 prime
  • 3 prime
  • GC content
  • AT content
  • melting temperature
  • pcr machine
  • thermocycler
  • annealing
  • dissociation
  • annealing temperature