Process Control in a Bioreactor for Culturing Cells

Process controls are used to maintain an optimal physical and chemical environment within a bioreactor (cell culture vessel used to incubate cells at a high density). This interactive scrollable explains what process controls are and why they are necessary to maintain optimal conditions for culturing cells in a bioreactor, reviews the different types of probes that are used to monitor the cell culture in a bioreactor, and describes how computer programs are used to monitor process variables and make automated adjustments to cell culture conditions in a bioreactor.

Topics

  • ALXCollab
  • biologic production
  • biologic
  • bioreactor
  • cell culture medium
  • cell culture
  • cell death
  • cell density
  • cell growth
  • cell viability
  • cell waste
  • drug substance technology
  • drug substance
  • environmental condition
  • growth condition
  • mAb
  • monoclonal antibody
  • offline procedure
  • probe
  • process control
  • process variable
  • real-time measurement
  • setpoint value
  • therapeutic protein production
  • therapeutic protein
  • waste product