Sex Determination in Humans

Explore how biological sex is determined in humans by learning about the role of the X and Y sex chromosomes as well as that of the sex-determining region Y (SRY) gene. You’ll also examine the sexual phenotypes of an individual with an abnormal number of sex chromosomes.

Topics

  • AMH
  • aneuploidy
  • anti-Müllerian hormone
  • autosomes
  • biological sex
  • chromosomal sex determination system
  • chromosomal variations
  • chromosomes
  • estrogen
  • female
  • female reproductive system
  • female sexual phenotype
  • fertilization
  • gene
  • genetic condition
  • genetic sex
  • gonads
  • homologous
  • hormones
  • humans
  • Jacob syndrome
  • Klinefelter syndrome
  • male
  • male reproductive system
  • male sexual phenotype
  • male-specific region of the Y chromosome
  • meiosis I
  • MSY
  • nonsex chromosomes
  • ovaries
  • PARs
  • pseudoautosomal regions
  • reproductive ducts
  • reproductive organs
  • sex
  • sex chromosomes
  • sex determination
  • sex determination system
  • sex reversal
  • sex-determining region of Y
  • sexual differentiation
  • sexual phenotype
  • SRY
  • SRY gene
  • SRY protein
  • testes
  • testosterone
  • Turner syndrome
  • undifferentiated gonads
  • X
  • X chromosome
  • XX
  • XX male
  • XX-XY
  • XY
  • XY female
  • XYY
  • Y
  • Y chromosome