In both type 1 and type 2 diabetes, glucose is unable to enter the cells, resulting in elevated levels of glucose in the blood. In type 1 diabetes, the beta cells in the pancreas are unable to produce insulin. Without insulin to create glucose channels, the glucose remains in the blood. Type 2 diabetes is the result of a combination of two factors: Cells become resistant to insulin, and the receptors can no longer bind the hormone. This text excerpt is from the Introduction of the ABE Student Guide.