Malaria and Sickle Cell Anemia: Putting an Old Hypothesis to the Test

Malaria and Sickle Cell Anemia: Putting an Old Hypothesis to the Test

Sickle cell trait provides a heterozygote advantage against malaria, exemplifying natural selection's impact on human genetics and disease resistance.

Topics

  • heterozygous
  • homozygous
  • heterozygote
  • natural selection
  • HbAS
  • Punnett square
  • autosomal
  • carrier
  • epidemiology
  • genotype
  • hemoglobin
  • heterozygote advantage
  • malaria
  • parasite
  • pedigree
  • phenotype
  • recessive inheritance pattern
  • sickle cell anemia
  • sickle cell trait