Formation of Phosphodiester Bond in DNA

Formation of Phosphodiester Bond in DNA

This animation shows the process of dehydration synthesis as a nucleotide is added to a DNA strand and how complementary base pairing is important to DNA synthesis.

Topics

  • phosphodiester bond
  • ester bond
  • phosphate group
  • 3’ hydroxyl
  • deprotonate
  • nucleotide
  • nucleophilic attack
  • deprotonated 3’ hydroxyl
  • alpha phosphate
  • electrophile
  • leaving group
  • pyrophosphate
  • thermodynamically