The muscular and skeletal systems provide support to the body and allow for a wide range of movement. The bones of the skeletal system protect the body’s internal organs and support the weight of the body. The muscles of the muscular system contract and pull on the bones, allowing for movements as diverse as standing, walking, running, and grasping items. Injury or disease affecting the musculoskeletal system can be very debilitating. In humans, the most common musculoskeletal diseases worldwide are caused by malnutrition. Ailments that affect the joints are also widespread, such as arthritis, which can make movement difficult and—in advanced cases—completely impair mobility. Progress in the science of prosthesis design has resulted in the development of artificial joints, with joint replacement surgery in the hips and knees being the most common. This pathway provides an in-depth look at types of skeletal systems; bone; joints & skeletal movement; muscle contraction & locomotion. The pathway also provides vocabulary support for these topics, as well as opportunities for learners to self-assess their understanding by analyzing figures and answering questions. Advanced Placement® and AP® are trademarks registered and/or owned by the College Board, which is not affiliated with, and does not endorse, this textbook.