This AP® Biology content explores how random events, population conditions, and mathematical models shape the genetic makeup and evolution of populations. Learners will investigate how population size, migration, mutation, mating patterns, and selection influence whether a population is evolving. Through interactive analysis and exploration of Hardy–Weinberg mathematical modeling, learners will describe how changes in these conditions impact genetic diversity, create differences between populations, and provide evidence for evolution over time. AP® is a registered trademark of the College Board, which has not reviewed this resource.