The Geographical Distribution of Human Genetic Variation

Historically, people thought that the human species could be divided into biological races based on the levels of genetic diversity between human populations. But is this true based on what we know about human genetic diversity? Let’s explore this question by looking at the geographical spread of genetic diversity across different populations.

References

Garte, S. (2009). Human population genetic diversity as a function of SNP type from HapMap data. American Journal of Human Biology, 22(3), 297–300. https://doi.org/10.1002/ajhb.20984 Holsinger, K. E., & Weir, B. S. (2009). Genetics in geographically structured populations: defining, estimating and interpreting FST. Nature Reviews Genetics, 10(9), 639–650. https://doi.org/10.1038/nrg2611 Parker, H. G., Kim, L. V., Sutter, N. B., Carlson, S., Lorentzen, T. D., Malek, T. B., Johnson, G. L., DeFrance, H. B., Ostrander, E. A., & Kruglyak, L. (2004). Genetic structure of the purebred domestic dog. Science, 304(5674), 1160–1164. https://doi.org/10.1126/science.1097406 Auton, A., Abecasis, G. R., Altshuler, D., Durbin, R., Bentley, D., Chakravarti, A., Clark, A. G., Donnelly, P., Eichler, E. E., Flicek, P., Gabriel, S., Gibbs, R. A., Green, E. D., Hurles, M. E., Knoppers, B. M., Korbel, J. O., Lander, E. S., Lee, C., Lehrach, H., . . . Schloss, J. A. (2015). A global reference for human genetic variation. Nature, 526(7571), 68–74. https://doi.org/10.1038/nature15393

Topics

  • health equity
  • public health
  • medical discrimination
  • equity
  • racism
  • inclusion
  • diversity
  • belonging
  • RDEISE
  • genetic variation
  • polymorphisms
  • allele
  • genetic diversity
  • biological races
  • genome project