Chromosomal Inheritance and Genetic Disorders

This AP® Biology pathway explores how chromosomal inheritance drives genetic variation in sexually reproducing organisms. Learners will examine how processes such as segregation, independent assortment, and random fertilization create diversity in offspring. They will also investigate how variations in chromosome number or structure, as well as single-gene mutations, can lead to genetic disorders. Through real-world examples, learners will see how the patterns of gene transmission influence traits in humans and other organisms. Coming soon: new interactive content on chromosomal mutations and small scale mutations. AP® is a registered trademark of the College Board, which has not reviewed this resource.

Topics

AP
AP Biology
AP Bio
next generation science standards
NGSS
sexual reproduction
polyploidy
chromosomal mutations
small scale mutations
chromosome
DNA
gene
meiosis
duplication
inversion
translocation
mutation
trisomy
aneuploidy